BORHEE Large Volume Magnetic Rack Selection Guide: Complete Solutions from 125 mL to 20 L

Application Scenarios and Selection Considerations for Large Volume Magnetic Racks

Main application areas:

- Cell therapy manufacturing: CAR-T, stem cell therapy, etc.

- Biopharmaceutical downstream processing: antibody purification, viral vector separation

- Industrial fermentation: microbial cell recovery

- Clinical-grade sample processing: cord blood banks, blood station operations

Key Selection Parameters

- Processing volume: routine sample volume range per run

- Processing frequency: batch interval and throughput requirements

- Cell type: sensitivity to shear stress

- Aseptic requirements: GMP grade or research grade

- Process integration: manual operation or automated integration

BORHEE Large Volume Magnetic Rack Product Matrix and Technical Parameters

Laboratory Series (125 mL - 1 L)

MAG-125-1 Compact rack | Container: 125 mL PE bottle | Separation time: 3-5 min | Cell recovery: >98% | Saves biosafety cabinet space | For process development and small-scale production

MAG-250-1 Compact rack | Container: 250 mL Shuniu bottle | Pole configuration: high-strength uniform combined poles for improved capture | Separation time: 3-5 min | Cell recovery: >98% | Saves biosafety cabinet space | For process development and small-scale production

MAG-250-3 Compact rack | Container: 250 mL Shuniu bottle | Separation time: 3-5 min | Cell recovery: >98% | Saves biosafety cabinet space | For process development and small-scale production

MAG-250-4 Compact rack | Container: 250 mL Shuniu bottle | Pole configuration: high-strength uniform combined poles for improved capture | Separation time: 3-5 min | Cell recovery: >98% | Saves biosafety cabinet space | For process development and small-scale production

MAG-500-1 Mid-size rack | Container: 250 mL Shuniu bottle | Pole configuration: dual-side poles for improved capture | Separation time: 3-5 min | Sorting efficiency: >98% (500 mL standard sample)

MAG-1L-1 Mid-size rack | Container: 1 L Shuniu bottle | Pole configuration: three-side poles for improved capture | Separation time: 3-5 min | Cell recovery: >98% | Saves biosafety cabinet space | For process development and small-scale production

MAG-1L-3 Mid-size rack | Container: 1 L Shuniu bottle | Pole configuration: high-strength uniform combined poles for improved capture | Separation time: 3-5 min | Cell recovery: >98% | Saves biosafety cabinet space | For process development and small-scale production

Pilot Production Series (2 L - 10 L)

MAG-2L-1 Mid-size rack | Container: 2 L Shuniu bottle | Pole configuration: three-side poles for improved capture | Separation time: 3-5 min | Cell recovery: >97% | Saves biosafety cabinet space | For process development and pilot production

MAG-2L-3 Mid-size rack | Container: 2 L Shuniu bottle | Pole configuration: high-strength uniform combined poles for improved capture | Separation time: 3-5 min | Cell recovery: >97% | Saves biosafety cabinet space | For process development and pilot production

MAG-5L-1 Mid-size rack | Container: 5 L Shuniu bottle | Pole configuration: three-side poles for improved capture | Separation time: 5-10 min | Cell recovery: >97% | Saves biosafety cabinet space | For process development and pilot production

MAG-5L-3 Mid-size rack | Container: 5 L Shuniu bottle | Pole configuration: high-strength uniform combined poles for improved capture | Separation time: 5-10 min | Cell recovery: >97% | Saves biosafety cabinet space | For process development and pilot production

Industrial Production Series (Above 10 L)

MAG-10L-3 Rack | Container: 10 L Shuniu bottle | Pole configuration: high-strength uniform combined poles for improved capture | Separation time: 5-10 min | Cell recovery: >97% | cGMP facility design | Automation-platform ready | For industrial production

MAG-20L-3 Rack | Container: 20 L Shuniu bottle | Pole configuration: high-strength uniform combined poles for improved capture | Separation time: 5-10 min | Cell recovery: >97% | Automation-platform ready | cGMP facility design | For industrial production

Selection Decision Workflow

Step 1: Define application requirements

- Determine processing volume: R&D < 1 L; pilot 1-10 L; industrial > 10 L

- Assess quality standards: research grade (basic function); clinical grade (GMP-compatible design); production grade (automation and data integrity)

Step 2: Match technical parameters

- Cell sensitivity analysis: sensitive cells (stem cells, primary cells) suit gentle magnetic field designs; tolerant cells (engineered cell lines) suit higher-efficiency models

- Process integration: standalone operation (basic models); semi-automated (interface-equipped models); fully automated (dedicated industrial models)

Step 3: Economic evaluation

- Initial investment budget; operating cost (energy, consumables, maintenance); ROI analysis (throughput gains, labor savings)

Step 4: Verification and confirmation

- Sample testing with your actual samples; regulatory compliance confirmation; evaluation of supplier training and technical support

Operation Optimization Tips

Magnetic field parameter optimization:

- For sensitive cells, high-strength uniform magnetic fields are recommended

- For high-density samples, extend separation time to about 120% of the recommended value

- For viscous samples, reduce flow rate to about 70% of the standard value

Process efficiency improvements:

- Batch pre-treatment: process multiple samples in parallel

- Standardized operation: establish SOPs to reduce operator variation

- Preventive maintenance: calibrate the magnetic field regularly to maintain peak performance

Quality Control Points

- Perform a system suitability test before each run

- Verify cell recovery and viability periodically

- Keep complete equipment usage and maintenance records

Future Upgrade Path

BORHEE large volume magnetic racks are designed with technology upgrades in mind:

- Modular expansion: larger volume designs can be added

- Automation upgrade: automation control modules can be added later

- Intelligent upgrade: smart monitoring and optimization systems can be integrated

Summary

Selecting the right large volume magnetic rack requires comprehensive consideration of technical parameters, application requirements and economic factors. BORHEE offers a complete product line from 125 mL to 20 L, with each model carefully designed and rigorously validated to deliver optimal performance in its intended application scenario.

From R&D to manufacturing, BORHEE large volume magnetic racks are a reliable partner for scaling up your cell sorting process, enabling a smooth transition from laboratory to clinical production.